The best way to start a home based business is by joining a Direct Sells Company. The expenses and overhead is low. There are 1,400 Direct Selling companies in the USA, many open new markets every year and worldwide an est. 10,000 Direct Selling companies are active with $250+ Billion in sales.
It depends also on what products of services you like, what kind of risk you want to take, as there is always a chance a company can go out of business, especially with starters, your motivation, if you need a lot of leadership, or if you are a self starter. Do you want to build local or global? The compensation plan can be a party plan or person-to-person. See 100 Top MLM Companies For 2020