HPV is very common and nearly everyone who is sexually active and doesn’t get the vaccine will get infected with it at some point in their lives, says the Centers for Disease Control and Prevention. It’s the most common sexually transmitted disease in the world, but it can also be spread skin-to-skin. Nearly 80 million Americans — most in their late teens and early 20s — have HPV, the CDC says. Girls, boys, young men and women, parents: the HPV vaccine helps to prevent cervical, anal, penile, vulvar, throat and esophageal cancers. Get More Information